Complexes of nanodiamonds with Gd-fullerenols for biomedicine: Fullerenes, Nanotubes and Carbon Nanostructures: Vol 0, No 0
Improvement of carbon-based buildings composed of nanoparticles with completely different kind of orbital hybridization of carbon (sp2, sp3) made it potential to create new substances with superior biomedical properties, luminescent, and magnetic when the carbon elements are modified by lanthanides for the purposes in Photodynamic Remedy or Magneto-Resonance Imaging. The offered outcomes are dedicated to the synthesis, physical-chemical and synchrotron research of water-soluble complexes of detonation nanodiamonds (particle dimension 4–5 nm) and fullerenols [email protected]82(OH)X (X ∼ 30). The affiliation of positively charged diamonds and electro-negative fullerenols created the complexes being steady beneath heating (25–70 °C) whereas the meeting of fullerenols with the diamonds carrying adverse floor expenses was much less possible. Small angle scattering of synchrotron radiation revealed the affiliation of diamonds into chain-like buildings extra steady as a result of further linking of diamonds through fullerenols. On account of complexing, fullerenols received magnetic resonance properties of adverse contrasting substances for MRI diagnostics. The checks on organic cells confirmed a low toxicity of complexes which can be utilized as potential biomedical supplies.